Detailed Product Description:
Dimethylformamide is a water-white combustible organic solvent.
Commonly used as a solvent for vinyl resins, and for organic synthesis,
often referred to as “DMF.” This colorless liquid is miscible with
water and the majority of organic liquids.
This is Reagent Grade material with 99% minimum purity.
DMF is a common solvent for chemical reactions. Its name is
derived from the fact that it is a derivative of formamide, the amide
of formic acid.
Dimethylformamide is a polar (hydrophilic) aprotic solvent with a high
boiling point. It facilitates reactions that follow polar mechanisms. It can
be synthesized from formic acid and dimethylamine. DMF is not stable in
the presence of strong bases like sodium hydroxide or strong acids such as
hydrochloric acid or sulfuric acid and is hydrolyzed back into formic acid
and dimethylamine, especially at elevated temperatures.
The primary use of dimethylformamide is as a solvent with a low evaporation
rate. It is used in the production of acrylic fibers and plastics. It is also used
as a solvent in peptide coupling for pharmaceuticals, in the development and
production of pesticides, and in the manufacture of adhesives, synthetic leathers,
fibers, films, and surface coatings.
DMF penetrates most plastics and makes them swell. It is therefore frequently
present as a component of paint strippers.
Reaction with sodium hydride in DMF as a solvent are somewhat hazardous;
exothermic decomposition has been reported at temperatures as low as 26 °C.
On a laboratory scale any thermal runaway is (usually) quickly noticed and
brought under control with an ice bath.
DMF has been linked to cancer in humans, and it is thought to cause birth
defects. In some sectors of industry women are banned from working with
DMF. For many reactions, it can be replaced with dimethyl sulfoxide. Most
manufacturers of DMF list (Life) or (Chronic) as a health hazard in their MSDS
since DMF is not readily disposed of by the body. According to IARC, DMF is
a possible carcinogen, although EPA does not consider it a cancer risk.
Combustible, moderate fire risk, explosive limits in air range from 2 to 13%.
Toxic by skin absorption and inhalation with a TLV = 10 ppm
Click here to download MSDS (Material Safety Data Sheet)
Comes packed in 500 ml boston round, amber glass bottle. Also available in 250ml size.